SPRAVATO®
Esketamine Nasal Spray
We Are Here For You
If you’ve taken two or more oral antidepressants and still experience symptoms of depression, you might have treatment-resistant depression (TRD).
It might be time to talk with us about a different treatment approach. See what makes SPRAVATO® different and learn more about other patients’ experiences with SPRAVATO®.
MASTOR MENTAL HEALTH
206 Joe V. Knox Avenue, Suite F
Mooresville, NC 28117
704-662-6500 Phone
704-662-6503 Fax
Dr. Jason Mastor
American Board Certified
in Psychiatry and Neurology
Spravato withMe
Spravato withMe is a savings program. The staff at MMH will work with you to enroll in the program and assist with a rebate (If applicable – commercial insurance).
SPRAVATO® is the only nasal spray treatment indicated for people who’ve taken two or more oral antidepressants and still experience symptoms of depression, or TRD
SPRAVATO® is an N-methyl-D-aspartate (NMDA) receptor antagonist that is believed to work differently by acting on a pathway in the brain where glutamate, a brain chemical, works with other brain chemicals to balance well-being and depression
Provider Referral
Please fill out the referral form and fax to PHC Mastor Mental Health at 704-662-6503
Additional Referral Information Packet
View Here
Self-Referral
If you are interested in the Spravato treatment, please call our office at 704-662-6500.
What to Expect
The first step is a consultation to determine if you are a candidate for Spravato treatment.
During this time, ask any questions you may have.- If you and the office decide to move forward with Spravato, a treatment plan will be put in place.
- Spravato treatment requires time commitment of 2 hours per treatment / 2x a week and a ride is required for each treatment
- Arrive at Mastor Mental Health and get settled in the treatment room. You will be laying on a comfortable chair for the duration of the treatment
- The spray is administered and you will be supervised for the 2 hours while the treatment is underway.
- After treatment, you will be groggy. You can’t do anything hazardous for the rest of your day. That includes operating a motor vehicle, so you’ll need someone to drive you home after treatment
- After 8 weeks of treatment, Dr. Mastor will determine the dosing frequency based on how you respond to it and how stable your response is.

Frequently Asked Questions
Spravato is a brand name for esketamine. Distinguished from traditional antidepressants, Spravato acts on the brain’s glutamatergic system, providing a new pathway for addressing the distressing symptoms of TRD and MDD. Importantly, Spravato has been FDA-approved specifically for TRD and MDD with suicidality, underscoring its scientific backing and rigorous testing. This therapeutic innovation opens a new chapter in mental health care, particularly for those patients who have not responded favorably to conventional treatment options.
The administration of Spravato at our clinic involves a structured procedure, under the supervision of a healthcare provider, ensuring patient safety is at the forefront. As a nasal spray, Spravato provides a non-invasive and relatively quick method of delivery. Patients can expect a thorough explanation and guidance throughout their treatment journey, ensuring transparency, comfort, and peace of mind.
Many major insurance companies cover ketamine-based depression treatment if you haven’t gotten better after trying just TWO antidepressants.
Videos
Spravato Testimonial